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What is Gonadorelin used for?
Gonadorelin (Levorelin) is used to increase the size and volume of the gonads (testicles or ovaries) in men with hypogonadism (inability to produce normal levels of male sex hormones).
Gonadorelin belongs to the same family of hormones as follicle-stimulating hormone (FSH). It is used to control male sex hormone production in men with hypogonadism. Hypogonadism is a condition in which a person is unable to produce sufficient amounts of hormones required for reproduction. Hypogonadism is characterized by low levels of FSH, the hormone that stimulates the production of androgens in the testes (testicles), including testosterone. There are many causes of hypogonadism, including autoimmune disease, hypothalamic disease, pituitary disease, or trauma to the brain or the pituitary gland that reduces or removes the ability of the hypothalamus to send a signal to the pituitary to produce FSH.
Does Gonadorelin increase testosterone?
A drug (Gonadorelin) is injected into the blood to increase the production and secretion of hormones. Gonadorelin also increases the number and size of the Leydig cells, which are the cells that produce testosterone. Gonadorelin is sometimes prescribed as a single shot or in 3-month cycles in which injection is repeated every three months for one to three years.
What gonadorelin dosage trt works?
When taken as directed, this medicine may help to increase the ability of the body to produce testosterone and sperm, help the penis to become erect, and make the testes to produce sperm. This medicine may not work in some men.
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Gonadorelin is a medicine that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland. GnRH causes the pituitary gland to release other hormones (luteinizing hormone [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults.
Gonadorelin stimulates the production and release of FSH and LH. FSH and LH help build and maintain the reproductive system of males and females. When administered to males, gonadorelin helps stimulate the production of sperm. In females, gonadorelin helps the egg to develop in the ovaries and prepare the uterus to be receptive to the fertilized egg.
How to use Gonadorelin?
To prepare for injection, inject the needle into the middle part of the thigh muscle or into the upper outer arm. Do not inject into the stomach, the back of the neck, or the buttocks. Avoid puncturing a blood vessel. Let the needle fall out when you are done. It is important to use a clean needle for each injection.
Do not inject into an area that is numb from a previous injection.
Do not use this medicine in children younger than 18 years.
This medicine is given by injection into muscle tissue, as opposed to being injected into a vein.
Gonadorelin injection is used for the treatment of infertility or poor ovarian function in females and for stimulation of sperm production in males.
This is a skin infection caused by bacteria and viruses. It may be a minor skin infection, such as a pimple or a bad cold sore. It may also be a more serious infection of the mouth, throat, sinuses, or eyes.
If you have a fever, cough, or breathing problem, seek medical care right away.
Do not use an antibiotic for this problem unless you are being treated by a doctor.
If you have any questions about whether you should use an antibiotic for a skin infection, speak with your doctor.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant before taking this medicine.
Is Gonadorelin a peptide?
This medicine is known to affect the way certain medicines work. Tell your doctor if you are using any other medicines, including any birth control pills or other medicines for hormone problems.
You may have a serious allergic reaction if you use this medicine. The chance of having a serious allergic reaction is greater if you have certain medical conditions such as asthma, hay fever, seasonal allergies, a previous history of allergies or severe eczema.
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Females of childbearing potential should tell their doctor if they plan on getting pregnant, planning to become pregnant, or are pregnant or breastfeeding.
Use caution if you drink alcohol. Drinking more than a couple of alcoholic beverages may cause you to become dizzy or lightheaded. Do not drink alcohol while taking this medicine.
If you are going to have surgery, tell the doctor or dentist that you are using this medicine.
Before you have any surgery or medical procedure, tell the doctor or dentist that you are using this medicine. This can help the doctor and dentist to prepare you and your surgical site for the safest possible surgery. You may be given medicine or general anesthesia during surgery.
If you have a blood clotting problem or any bleeding problem, tell the doctor before you take this medicine.
If you are taking a vitamin or mineral supplement or medication that contains iron, tell your doctor if you plan to take this medicine. It is not known if this combination will harm your health.
Females who are using birth control pills or other medicines that affect hormone levels may have an increased chance of getting pregnant. If you plan to become pregnant or if you are pregnant, you should use additional forms of birth control (e.g., barrier methods of birth control, such as condoms and diaphragms, and spermicide).
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You may be more likely to have a blood clot or blood clots in your lungs (pulmonary embolism).
This medicine can make you more likely to get a serious infection or to have a stroke. Make sure you know the signs of a stroke and where you can get help right away.
Ask your doctor before you use a hormone therapy patch (transdermal), gel, or cream for skin problems.
If you are taking birth control pills and you need emergency contraception (Plan B One-Step or ella) in the middle of a period, wait 3 days after the first period you have had in the past 3 months has ended.
If you have diabetes or are taking insulin, tell your doctor if you plan to take this medicine.
Gonadorelin side effects
Gonadorelin side effects can include:
An abnormal feeling of pressure in the head or around the chest, and chest pain or pain.
Gonadorelin injection may interfere with glucose (sugar) levels in the blood. Do not have an insulin shot (such as an insulin pump) unless your doctor tells you to do so. Check with your doctor before having another insulin shot if you are not using a diabetes medicine.
If you have diabetes and are taking insulin or other medicines to control your blood sugar, tell your doctor before you use gonadorelin injection. Do not use more of this medicine than you would use for the treatment of your diabetes.
Do not give this medicine to a child younger than 18 years without the advice of a doctor.
If you are breastfeeding or are planning to breastfeed, do not use this medicine.
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It is not known if gonadorelin injection passes into breast milk. Do not use it without the advice of a doctor. Use of this medicine while breastfeeding may result in decreased milk supply or breastfeeding problems.
Females who are using birth control pills or other medicines that affect hormone levels may have an increased chance of getting pregnant. If you plan to become pregnant or if you are pregnant, you should use additional forms of birth control (e.g., barrier methods of birth control, such as condoms and diaphragms, and spermicide).
Call your doctor right away if you have pain in your eyes.
Ask your doctor before using any medicine that can be taken by mouth, if you have trouble swallowing.
Females who are using birth control pills or other medicines that affect hormone levels may have an increased chance of getting pregnant. If you plan to become pregnant or if you are pregnant, you should use additional forms of birth control (e.g., barrier methods of birth control, such as condoms and diaphragms, and spermicide).