Matrixyl Buy Online for research use only.
Matrixyl (palmitoyl pentapeptide-3) for sale here at the amazing price of $200.00
Does Matrixyl 3000 Really Work?
The original Matrixyl is Palmitoyl Pentapeptide-4 and Matrixyl that is Palmitoyl Pentapeptide-6 are isolated from the natural sources. The two forms are identical in primary structure but may differ in the stereochemical configuration at the alpha-amino and alpha-carboxy termini.
Is Matrixyl better than retinol?
The two naturally occurring matrixyl peptides, i.e., palmitoyl pentapeptide-4 (P-4) and palmitoyl pentapeptide-6 (P-6), are isolated as optically pure form from mollusks. Palmitoyl pentapeptide-4 is a pentapeptide of the sequence of L-Pro-D-Leu-D-Leu-L-Asp-L-Leu-L-Val-L-Ser-OH and palmitoyl pentapeptide-6 is a hexapeptide of the sequence of L-Pro-D-Leu-D-Leu-L-Asp-L-Leu-L-Val-L-Ser-D-Leu-L-Val-L-Ser-D-Leu-L-Val-L-Ser-D-Leu-L-Val-L-Ser-D-Leu-L-Val-L-Ser-D-Leu-L-Val-L-Ser-OH, wherein the L-isomer forms the optically pure configuration.
Matrixyl benefits
P-4 and P-6 have many physical properties similar to the original matrixyl peptide including the ability to form micelles, the ability to cause phase transition, and the ability to interact with cholesterol. In addition, palmitoyl pentapeptide-4 has a very broad spectrum of biological activities. For example, P-4 inhibited the platelet-aggregating action of arachidonic acid, inhibited binding of fibrinogen to the platelet receptor site and its associated platelet aggregation, and was effective in preventing the formation of venous thrombosis, neointimal proliferation in arteries, and in reversing hypertension.
The ordinary matrixyl how to use
The palmitoyl groups play an important role in the biological activities of P-4 and P-6. This is clearly demonstrated by the effects of the removal of these groups as well as by the removal of both of them. When the palmitoyl groups are removed from either P-4 or P-6, the in vitro activities of the resulting peptides are significantly reduced. This would suggest that these biologically active portions of P-4 and P-6 must be in the configuration of the free acids. Thus, this study demonstrates that the original matrixyl peptide is more active than either P-4 or P-6 and the configuration of the active portion of the peptide is D-amino acid or L-amino acid.
The ordinary matrixyl how to use
However, the activity of P-4 and P-6 is still higher than that of an equivalent amount of matrixyl itself. For example, the effect of P-4 is equivalent to the effect of 2.7 times of matrixyl.
Matrixyl and Niacinamide
The activities of the individual pentapeptides of P-4 and P-6 are the following
Matrixyl Buy Online
The original matrixyl can be in L- or D-configuration. If the matrixyl is in D-configuration, it may be of the type described by Vyas et al., U.S. Pat. No. 4,670,417 and by G. E. Vyas and N. J. Lidicker, “Chemistry of Natural Peptides”, Academic Press, 1978, p. 13-22. Furthermore, in the presence of Ca++, L-matrixyl will convert to D-matrixyl.
