Gonadorelin For Sale here today for educational and research use only.
Is Gonadorelin a peptide?
Gonadorelin is a research peptide that is the same as gonadotropin-releasing hormone (GnRH) that is naturally released from the hypothalamus gland. GnRH causes the pituitary gland to release other hormones (luteinizing hormone [LH] and follicle-stimulating hormone [FSH]). LH and FSH control development in children and fertility in adults. Gonadorelin helps fertility and helps with menopausal symptoms. It is used for women who have low estrogen levels, have a history of multiple abortions, and have not responded to previous hormone treatments.
Gonadorelin For sale as:
- An injectable solution of gonadorelin (for subcutaneous injection)
- A topical ointment
For more information about the medication, see PRECAUTIONS: PRECAUTIONS OF KNOWN EFFECTS, SPECIAL SENSITIVITY (ADVERSE REACTIONS), DRUG INTERACTIONS (ADVERSE REACTIONS), DRUG SIDE EFFECTS, and DOSAGE AND ADMINISTRATION.
How do you administer Gonadorelin?
For an oral tablet, an injectable, a topical ointment, or a topical vaginal ring, see FDA Product Information on Contraceptives and Hormone Replacement Therapy.
Tablets, Oral Solution, or Gel
Do not use it in pregnancy or during lactation. Female patients of childbearing potential should use effective contraception during treatment with this medicine and for at least 2 months after the last dose. Do not use it in children.
Gonadorelin Side Effects?
Drugs used in the treatment of endometriosis or polycystic ovary syndrome may cause serious adverse reactions when used with gonadorelin.
ADVERSE REACTIONS
Adverse reactions have been reported. Serious adverse reactions may be life-threatening and can include: blood clots, stroke, cardiovascular problems, and a condition called tumor lysis syndrome. Consult your doctor for more information.
PRECAUTIONS
Pregnancy
If a woman is planning to become pregnant or is pregnant, gonadorelin should be used only when clearly needed and strictly according to the instructions provided by your doctor. The safety of gonadorelin in pregnancy is not known. If used in a woman who is pregnant, gonadorelin may cause an abortion. Gonadorelin should be used with caution if there is a risk of miscarriage (loss of early pregnancy or spontaneous abortions). Gonadorelin is not indicated for the treatment of ovulation disorders or menstrual disorders. It is contraindicated for women with active, severe systemic lupus erythematosus, or when gonadorelin is used as a contraceptive.
Severe hypersensitivity to this drug has been reported. A severe allergic reaction, e.g., anaphylaxis, occurs in less than 1% of patients receiving gonadorelin. Closely monitor patients for symptoms of hypersensitivity during therapy with gonadorelin. Discontinue gonadorelin therapy if an allergic reaction occurs. Injections should be given using medical facilities equipped to deal with anaphylactic reactions.
Contraceptive Effects
Gonadorelin should be used to support fertility in a natural cycle only. Do not use it to prevent pregnancy (contraception). It should be used with caution in women of childbearing potential who do not wish to become pregnant. If you are a woman of childbearing potential (including adolescents), plan your pregnancy carefully. Do not assume that you will be pregnant because you are being treated with this drug. Consult your doctor if you are not certain of your pregnancy status (See PRECAUTIONS).
Do not use an injectable solution of gonadorelin for injection in women who are or plan to become pregnant. Gonadorelin is used only to support fertility. Do not use it to prevent pregnancy (contraception). It should be used with caution in women of childbearing potential who do not wish to become pregnant. If you are a woman of childbearing potential (including adolescents), plan your pregnancy carefully. Do not assume that you will be pregnant because you are being treated with this drug.
Ovulation Disorder
Use gonadorelin only to help women ovulate or to induce ovulation. Do not use to prevent pregnancy (contraception). Do not use this drug to support ovulation in women whose ovulation is not controlled by medications. If you are being treated for an ovulation disorder, you should follow your doctor’s instructions carefully. Do not increase the frequency of your menstrual periods.
Is there a High Risk of a Heart Attack?
Gonadorelin should be used only to help support fertility in women at high risk for a heart attack or who have a history of heart disease. Gonadorelin should be used with caution in women with a history of a previous myocardial infarction, angina, coronary bypass surgery, angioplasty, or stroke. Do not use gonadorelin in the following conditions:
- Uncontrolled hypertension,
- Myocarditis or cardiomyopathy (in patients with previous heart disease),
- Sudden, unexplained, severe weakness,
- Any disease that may lead to sudden cardiac arrest (e.g., ventricular tachycardia or cardiac arrest).
Gonadorelin For Sale and Important Safety Information
Interactions:
Do not use in combination with GnRH agonists, other gonadotropin-releasing hormones, GnRH analogs, or GnRH-receptor antagonists. The use of GnRH agonists and analogs, and GnRH antagonists may increase the risk of bone loss in women taking gonadorelin.
Caution is advised in patients with a history of diabetes, hypertension, cardiovascular disease, coronary disease, or in those with hyperlipidemia or a tendency to hyperlipidemia.
Use caution in patients with a history of heart disease or arrhythmias.
Take care when giving a dose of gonadorelin subcutaneously in women of childbearing potential.
Use caution in elderly patients, patients with a history of a recent heart attack or stroke.
Do not administer to women in labor, those with risk factors for the acute coronary syndrome, or patients with myocarditis, pericarditis, or unexplained prolonged QTc interval.
Take care with gonadorelin in patients with risk factors for cardiovascular disease (e.g., hypertension, hyperlipidemia), or a history of cardiovascular disease (e.g., coronary artery disease, myocardial infarction, angina, stroke, and transient ischemic attack).
Gonadorelin For Sale for research use only and is not for use on humans.
