If you want to buy Nolvadex PCT you need to read on and learn the secrets for Post Cycle Therapy. PCT refers to an aspect of hormone replacement therapy (HRT). In other words, HRT, PCT or PCT/HRT is a program or series of steps used to treat an individual following a cycle of a primary drug.
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HRT can have many different phases, for example, a “normal phase,” during which an individual receives estrogen, progestin, and testosterone, and “a rebound phase,” during which an individual who has received estrogen and progestin during a previous “normal phase” is also given testosterone to counteract the estrogen and progestin. The primary goal of the “normal phase” is to prevent an individual’s body from going into “rebound,” during which an individual has a decrease in bone mineral density, thus resulting in additional calcium requirements.
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Post cycle therapy (PCT) is the practice of administering additional drugs to mitigate the effects of drugs and other treatments that a patient has received, and to prevent the patient from experiencing the undesirable effects of those drugs. Post cycle therapy is used in an attempt to treat an individual for possible detrimental side effects and to facilitate a natural recovery process.
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HRT may be utilized to prevent undesirable effects or side-effects associated with primary drug administration, for example, to prevent bone loss during estrogen treatment or to minimize a recurrence of the vaginal symptoms experienced by post menopausal women who have undergone a hysterectomy. Such adverse effects of primary drug administration include bone mineral density loss, bone fracture, uterine bleed, mood changes, headache and depression, breast tenderness and an increase in hot flashes.
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In addition, for a patient undergoing breast cancer treatment, such as with a primary drug having known carcinogenic side effects, the administration of additional drugs may prevent or minimize a recurrence of breast cancer. Additionally, the administration of additional drugs may reduce the effects of the primary drug and aid the patient in recuperating from chemotherapy and radiation therapy and from other drug therapies that may be administered in combination with the primary drug.
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Post cycle therapy has been used to reduce negative side effects of various primary drugs including, but not limited to: estrogen; estrogen/progestin combination drugs; and anti-androgen drugs. Estrogen and estrogen/progestin combination drugs are used for treatment of primary conditions, such as: gynecological conditions including but not limited to breast cancer, endometriosis, ovarian cysts, benign breast disease, dysfunctional uterine bleeding, benign breast disease and pelvic inflammatory disease; cardiovascular conditions such as but not limited to atherosclerosis, cardiovascular disease, hypertension, obesity, and dyslipidemia; endocrine conditions including but not limited to: infertility and reproductive conditions such as, sexual dysfunction and dysfertility, premenstrual syndrome, premenstrual dysphoric disorder and endometriosis; hematologic conditions such as but not limited to thrombosis, thromboembolic disease, hematologic disorders, including, but not limited to: thrombocytopenia, aplastic anemia, and myelodysplastic syndrome; infectious disease and infectious disorders such as, HIV, herpes, gonorrhea, genital infection, HIV, hepatitis, syphilis, and the like. Post cycle therapy also may be used in combination with anti-androgen drugs for treatment of primary conditions such as acne, benign prostate hypertrophy, and hirsutism.
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While effective in reducing negative side effects associated with primary drug administration, post cycle therapy may have the side effect of increasing the risk of endometrial cancer. One theory regarding the increased risk of endometrial cancer is that estrogen may actually stimulate proliferation and growth of cells. Thus, a reduction in estrogen has been shown to reduce the growth and proliferation of breast cancer cells. Post cycle therapy, by reducing estrogen, can prevent the growth and proliferation of the breast cancer cells.
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Additionally, estrogen is known to reduce the growth and proliferation of the endometrial cells. By reducing the estrogen levels associated with PCT/HRT, the risk of endometrial cancer associated with this therapy can be reduced or eliminated. An individual may be treated with HRT alone for conditions not involving primary diseases. Examples of HRT treatment for this purpose include treatments for depression, anxiety, and pain, for example. Other indications for HRT include the prevention of atherosclerosis and thrombosis.
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For conditions related to primary diseases, HRT may be used to treat conditions that are known to be associated with estrogen and/or progestin treatment, for example conditions associated with high estrogen and/or progestin levels, for example. The following discussion details examples of conditions that may be treated with HRT, and the primary drugs used to treat those conditions.
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The following discussions of various primary drugs associated with HRT for primary diseases are for illustrative purposes only and are not meant to limit the scope of the claims of the present application. Other primary drugs that may be associated with PCT/HRT are referred to in the art.
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Additionally, other diseases that may be treated with the following secondary drugs and/or conditions are known and/or are described in the art. HRT may be utilized to treat diseases associated with high estrogen or progestin levels. These diseases include, but are not limited to: endometriosis, dysmenorrhea, dysfunctional uterine bleeding, premenstrual syndrome, premenstrual dysphoric disorder, benign breast disease, ovarian cysts, fibrocystic breast disease, and uterine fibroids.
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A primary drug that reduces the level of estrogen in the body is referred to as an “estrogen antagonist” and is typically administered to prevent the undesirable effects that may occur as a result of a primary drug having high estrogen levels. A primary drug that reduces the level of progestin in the body is referred to as a “progestin antagonist” and is typically administered to prevent the undesirable effects that may occur as a result of a primary drug having high progestin levels.
Estrogen antagonists may include progestin-like compounds such as lynestrenol. Estrogen antagonists are also available that are selective for particular estrogens. The administration of estrogen antagonists can have the effect of mimicking or antagonizing the effects of an estrogen. For example, administration of estrogen antagonists can reduce the adverse effects of an estrogen antagonist on a target organ, by either reducing estrogen levels in the target organ or by increasing the effect of the estrogen on the target organ. Estrogen antagonists have also been shown to reduce the adverse effects of estrogen on the heart. Estrogen antagonists also have been shown to reduce the adverse effects of an estrogen on the brain.
